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Middle East Current Psychiatry

Table 5 ROC curve analysis of sensitivity and specificity of C-reactive protein (CRP) serum level in diagnosis of MDD

From: C-reactive protein as a biomarker for unipolar versus bipolar depression: a cross-sectional study

 

AUC

SEa

95% CI

Sensitivity

Specificity

Cutoff value

P-valueb

CRP in patients with MDD

0.988

0.006

0.969– > 0.999

86.7%

96.7%

 ≥ 107.30

 < 0.001*

CRP in patients with BD

0.994

0.006

0.984– > 0.999

93.3%

96.7%

 ≥ 106.50

 < 0.001*

  1. AUC Area under the curve, SE Standard error, CI Confidence interval of AUC
  2. a Under the nonparametric assumption
  3. b Null hypothesis: true area = 0.5
  4. *P-value < 0.05 is considered significant
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