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Table 1 Comparison of depression and suicide scores during intravenous ketamine sessions

From: A prospective open-label study to evaluate the effectiveness of intravenous ketamine as an adjunct in treating severe depression

Sl. no.

Rating scale

Baseline

Session 2

Session 3

Session 4

Session 5

Mean (SD)

Mean (SD)

p-value

Mean (SD)

p-value

Mean (SD)

p-value

Mean (SD)

p-value

1

MADRS

43.1 (8)

29.6 (13.1)

< 0.001

19.4 (13)

< 0.001

10 (10.5)

< 0.001

3.5 (7.3)

< 0.001

2

HAMD

32.8 (9.8)

21.1 (9.6)

< 0.001

12.7 (9.1)

< 0.001

6.7 (7.4)

< 0.001

3.6 (6.7)

< 0.001

3

MSSI

25.9 (8.6)

14.3 (10.7)

< 0.001

6.3 (8.7)

< 0.001

2.3 (6.3)

< 0.001

0 (0)

< 0.001

  1. MADRS Montgomery-Asberg Depression Rating Scale: HAMD Hamilton Rating Scale for Depression: MSSI Modified Scale for Suicidal Ideation: test used, Wilcox sign-rank test; p-value < 0.001 is highly significant