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Middle East Current Psychiatry

Table 2 Case of a patient with TRD who meets the clinical criteria for treatment with esketamine nasal spray plus an SSRI/SNRI

From: Management of treatment-resistant depression with esketamine nasal spray: clinical questions for daily practice in Gulf Cooperation Council countries

• Fifty-year-old male

• Three previous episodes of depression; currently experiencing a relapse that has not responded to treatment with three different antidepressants, including an SSRI and an SNRI, and augmentation with quetiapine

• Current depressive symptoms are moderate-to-severe in nature and are impacting the patient’s functioning

• No clinically significant or unstable cardiovascular or respiratory conditions

• No other relevant comorbidities

  1. SNRI serotonin and norepinephrine reuptake inhibitor, SSRI selective serotonin reuptake inhibitor, TRD treatment-resistant depression
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