Fig. 2From: Management of treatment-resistant depression with esketamine nasal spray: clinical questions for daily practice in Gulf Cooperation Council countriesProposed MDD treatment algorithm. Figure adapted from Kasper S, et al. 2021 [11]. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any wayMDDÂ major depressive disorder, SNRIÂ serotonin and norepinephrine reuptake inhibitor, SSRIÂ selective serotonin reuptake inhibitorBack to article page