Table 5 Summary of the outcome of studies conducted with MSCs
From: Cell therapies for autism spectrum disorder: a systematic review of clinical applications
| Â | Sharifzadeh et al. [77] | Sun et al. [87] |
|---|---|---|
CARS | No significant difference | - |
GARS-II | No significant difference | - |
PDDBI | - | Improvement in 5/12 |
CGI-I | No significant difference | Much improvement in 1/12 Minimal improvement in 8/12 No improvement in 3/12 |
CGI-S | Improved significantly | |
Daily skills (VABS) | No significant difference | Improvement in 6/12 |
Learning skills (PDDBI) | No significant difference | Improvement in 5/12 |
Relationship to people | Improved significantly | - |
Social interaction (VABS) | No significant difference | Improvement in 6/12 |
Adaptive behavior (VABS) | No significant difference | Improvement in 6/12 |
Verbal cognitive ability | No significant difference | - |
Motor skills (VABS) | No significant difference | Improvement in 6/12 |
Body usage | Improved significantly | - |
Major adverse events | None | 2 |