Table 2 Neuropsychiatric manifestations, anti-ribosomal P protein level, and brain MRS findings in the study SLE patients (n = 50)
Characteristic | SLE patients (n = 50) |
|---|---|
Neurological manifestations, n (%) | |
Headache | 20 (40) |
Psychosis | 12 (24) |
Seizures | 6 (12) |
Polyneuropathy | 6 (12) |
Acute confusional state | 6 (12) |
Cerebrovascular accidents | 2 (4) |
Myelopathy | 0 |
Movement disorders | 0 |
Aseptic meningitis | 0 |
Demyelinating syndrome | 0 |
Autonomic neuropathy | 0 |
Myasthenia gravis | 0 |
Psychiatric scores | |
HAM-D, n (%) | |
Negative | 29 (58) |
Mild | 15 (30) |
Moderate | 6 (12) |
HARS | |
Negative | 25 (50) |
Mild to moderate | 13 (26) |
Moderate to severe | 12 (24) |
MMSE, M ± SD | 28.98 ± 1.38 |
W. logical memory, M ± SD | 14.48 ± 5.27 |
W. digits forward, M ± SD | 4.78 ± 1.58 |
W. digits backward, median (min–max) | 3 (0–5) |
Anti-ribosomal P protein antibody (units/ml), median (min–max) | 13 (2.5–88.7) |
MRS measurements in the posterior cingulate gyrus, M ± SD | |
NAA/Cr | 1.61 ± 0.23 |
Cho/Cr | 0.97 ± 0.19 |
mI/Cr | 0.53 ± 0.10 |