Effect of intranasal oxytocin combination therapy with applied behavior analysis on social impairments in pediatric’s children with autism spectrum disorder

Middle East Current Psychiatry

Table 3 Strengths and difficulties questionnaire (SDQ) mean scores

Variable	Time	INT-OXT	NS	Between groups	Follow-up time	Interaction (time × group)
Parent SDQ mean scores	Baseline	51.3 ± 2.7	51.4 ± 3.3	p < 0.001	p < 0.001	p < 0.001
	Treatment onset	50.4 ± 2.5	51.4 ± 3.9
	Treatment ending	48.1 ± 2.3	51.6 ± 3.2
	Ending follow-up	46.8 ± 3.3	50.4 ± 3.9
Teacher SDQ mean score	Baseline	60.3 ± 3.7	52.2 ± 4.2	p < 0.05	p < 0.001	p < 0.05
	Treatment onset	51.8 ± 3.8	52 ± 3.7
	Treatment ending	49.7 ± 3.7	51.4 ± 3.2
	Ending follow-up	46 ± 3.2	49.7 ± 3.1

INT-OXT intranasal oxytocin, NS normal saline. Categorical data were compared using chi-square, and the repeated-measure ANOVA model was used for continuous parameters