Table 2 clinical profile of patients on clozapine
Diagnosis | No of patients (n)/percentage (%age) |
|---|---|
Treatment-resistant schizophrenia | 66 (75.0) |
Treatment-resistant schizoaffective disorder | 5 (5.7) |
Treatment resistant bipolar disorder | 5 (5.7) |
Schizophrenia with suicidality | 6 (6.8) |
Tardive dyskinesia | 3 (3.4) |
Parkinsonism with psychotic features | 1 (1.1) |
Neuroacanthocytosis | 1 (1.1) |
Psychotic depression | 1 (1.1) |
Comorbidity | |
 None | 81 (92.0) |
 Hypothyroidism | 4 (4.5) |
 Hypertension | 1 (1.1) |
 Diabetes mellitus | 1 (1.1) |
 Parkinsonism | 1(1.1) |
No. of antipsychotics used prior to clozapine | |
 2 (two) | 38 (43.2) |
 > 2 (more than two) | 50 (56.8) |
Antipsychotic used prior to clozapine | |
 Haloperidol | 66 (75) |
 Chlorpromazine | 2 (2.3) |
 Olanzapine | 65 (73.9) |
 Risperidone | 34 (38.6) |
 Amisulpride | 11 (12.5) |
 Quetiapine | 5 (5.7) |
 Aripiprazole | 4 (4.5) |
 Paliperidone | 1 (1.1) |
Dose range of clozapine (in mgs) | |
 <= 100 mgs | 5 (5.7) |
 101–200 mgs | 22 (25.0) |
 201–300 mgs | 21 (23.9) |
 301–400 mgs | 22 (25.0) |
 401–500 mgs | 11 (12.5) |
 501–600 mgs | 3 (3.4) |
 > 600 mgs | 4 (4.5) |