Effect of long-term administration of clonazepam, carbamazepine, and valproate on cognitive, psychological, and personality changes in adult epilepsy: a case–control study

Middle East Current Psychiatry

Table 3 The Wechsler Adult Intelligence Scale among the studied samples

Variables	Group 1 N = 35 Mean ± SE	Group 2 N = 18 Mean ± SE	Group 3 N = 31 Mean ± SE	Group 4 N = 15 Mean ± SE	Group 5 N = 40 Mean ± SE	P value
Verbal IQ	79.35 ± 0.56	81.5 ± 0.45	80.8 ± 0.8	79.8 ± 0.2	87.3 ± 0.4	0.001*
Performance IQ	92.41 ± 0.71	92 ± 0.91	88.96 ± 0.8	91 ± 0.67	94 ± 0.8	0.007*
Total IQ	83.02 ± 0.4	84.6 ± 1.4	82.3 ± 0.5	82.2 ±0.106	89.6 ± 0.5	0.108
DI	9.12 ± 1.3	8.9 ± 2.06	9.16 ± 1.24	9.05 ± 2.9	1.16 ± 1.38	0.001*

Group 1: carbamazepine, group 2: valproate, group 3: carbamazepine and clonazepam, group 4: valproate and clonazepam, group 5: epileptic patients without antiepileptic drugs (AEDs), *significant P value, DI Deterioration Index